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Updated: Jul 6, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
09:20

CRISPR-Mediated Reorganization of Chromatin Loop Structure

Published on: September 14, 2018

通过抑制多染色体关节分子的形成,BLM ortholog,Sgs1可以防止异常交叉

Steve D Oh1, Jessica P Lao, Patty Yi-Hwa Hwang

  • 1Section of Microbiology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.

Cell
|July 31, 2007
PubMed
概括

布鲁姆旋酶 (BLM) 通过破坏异常的关节分子,在半分裂过程中防止有害的DNA交叉. 这种机制确保了有效的DNA修复,同时最大限度地降低了与交叉交叉相关的风险.

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