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Updated: May 5, 2026

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
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Published on: February 27, 2018

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在亨廷顿病中,全球变化对全域素系统的变化

Eric J Bennett1, Thomas A Shaler, Ben Woodman

  • 1Department of Biological Sciences, Stanford University, Stanford, California 94305, USA.

Nature
|August 10, 2007
PubMed
概括

亨廷顿氏病 (HD) 涉及到多基因链的脑积累,表明基因蛋白酶系统 (UPS) 功能受损. 这种功能障碍是HD病理的早期和一致特征,在小鼠模型和人类患者中都是如此.

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