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Updated: Jul 5, 2026

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
10:06

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

hCAS/CSE1L与染色质相关,并调节选择p53向基因的表达

Tomoaki Tanaka1, Shuichi Ohkubo, Ichiro Tatsuno

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Cell
|August 28, 2007
PubMed
概括

人类细胞亡敏感性蛋白 (hCAS/CSE1L) 结合特定的基因促进体,影响p53介导的转录和细胞结局,如亡. 它的下调影响基因表达和基因素甲基化.

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Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter06:59

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