Jove
Visualize
联系我们

相关概念视频

Position-effect Variegation02:32

Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Exon Recombination02:32

Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon has three reading...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.

Blood·2022
Same author

Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.

Nature communications·2018
Same author

Measurement of the inclusive jet cross section in pp collisions at √s = 7 TeV.

Physical review letters·2011
Same author

Measurement of the polarization of W bosons with large transverse momenta in W + jets events at the LHC.

Physical review letters·2011
Same author

Search for neutral minimal supersymmetric standard model Higgs bosons decaying to tau pairs in pp collisions at √s=7 TeV.

Physical review letters·2011
Same author

Measurement of the B0 production cross section in pp collisions at sqrt[s] = 7 TeV.

Physical review letters·2011
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jul 9, 2026

Quantitative Comparison of cis-Regulatory Element (CRE) Activities in Transgenic Drosophila melanogaster
08:19

Quantitative Comparison of cis-Regulatory Element (CRE) Activities in Transgenic Drosophila melanogaster

Published on: December 19, 2011

在Drosophila melanogaster中双胸复合体的分子遗传学

W Bender, M Akam, F Karch

    Science (New York, N.Y.)
    |July 1, 1983
    PubMed
    概括

    果中的 bithorax 复合体控制着身体部分的发育. 研究人员绘制了195,000个基对,发现突变通常涉及DNA重组和"吉普赛"移动元素.

    科学领域:

    • 发展生物学 发展生物学
    • 遗传学 是一个遗传学.
    • 分子生物学分子生物学

    背景情况:

    • 在Drosophila melanogaster中, bithorax复合体对于指定体段发育至关重要.
    • 了解它的遗传组织和突变机制是发展生物学的关键.

    研究的目的:

    • 为了描述比索拉克斯复杂DNA的195,000个基对区域.
    • 为了确定这个复合体内的突变的性质.

    主要方法:

    • 对 bithorax 综合体的 DNA 隔离和表征.
    • 在突变者中识别DNA重组和移动元素插入.

    主要成果:

    • 分析了比索拉克斯复合体左半部分的195,000个基对区域.
    • 大多数bithorax复杂突变都是DNA重组的结果.
    • 移动元素"吉普赛"经常被插入到自发突变中,影响基因功能.

    结论:

    • DNA重组,特别是"吉普赛"插入,是生物复杂突变的主要原因.
    • 突变病变可以跨越很长的DNA距离,表明复杂的调节相互作用.

    更多相关视频

    Recombineering Homologous Recombination Constructs in Drosophila
    14:23

    Recombineering Homologous Recombination Constructs in Drosophila

    Published on: July 13, 2013

    Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches
    08:33

    Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches

    Published on: October 17, 2019

    相关实验视频

    Last Updated: Jul 9, 2026

    Quantitative Comparison of cis-Regulatory Element (CRE) Activities in Transgenic Drosophila melanogaster
    08:19

    Quantitative Comparison of cis-Regulatory Element (CRE) Activities in Transgenic Drosophila melanogaster

    Published on: December 19, 2011

    Recombineering Homologous Recombination Constructs in Drosophila
    14:23

    Recombineering Homologous Recombination Constructs in Drosophila

    Published on: July 13, 2013

    Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches
    08:33

    Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches

    Published on: October 17, 2019