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Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Proofreading01:31

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Variance01:15

Variance

The deviations show how spread out the data are about the mean. A positive deviation occurs when the data value exceeds the mean, whereas a negative deviation occurs when the data value is less than the mean. If the deviations are added, the sum is always zero. So one cannot simply add the deviations to get the data spread. By squaring the deviations, the numbers are made positive; thus, their sum will also be positive.The standard deviation measures the spread in the same units as the data.

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相关实验视频

Updated: Jul 1, 2026

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

这就是Erratum Erratum.

    Science (New York, N.Y.)
    |August 7, 1987
    PubMed
    概括

    对一份关于T偶菌体的报告进行了纠正. 这项研究发现,nrdB 内基因发生变化,这表明这些菌体基因组内的移动性.

    科学领域:

    • 分子生物学分子生物学
    • 病毒学 病毒学
    • 遗传学 遗传学 是一个

    背景情况:

    • 佩德森-莱恩和贝尔福特撰写的报告"nrdB内在T均菌体中的可变发生表明内流动性"包含印刷错误.
    • 准确的科学报告对于传播分子生物学和病毒学研究成果至关重要.

    研究的目的:

    • 从原始报告中提供纠正的句子.
    • 确保准确地了解T-均菌体中的内子同质学和实验方法.

    主要方法:

    • 在公布的报告中纠正特定句子.
    • 引用预先信使RNA (预先mRNA) 的杂交和二氧化原始扩展分析.
    • 澄清数字传说中使用的寡核酸探针描述.

    主要成果:

    • 在整个T-偶菌体中,td内是同类的.
    • 实验验证涉及杂交和原料扩展分析.
    • 对于实验的可重复性而言,寡核酸探针被明确定义.

    结论:

    • 修正后的信息澄清了T-偶菌体中td内的同质性.
    • 准确的方法描述对于验证关于内部流动性的发现至关重要.

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