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相关概念视频

ATP Driven Pumps II: P-type Pumps01:34

ATP Driven Pumps II: P-type Pumps

The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
Actin Treadmilling01:18

Actin Treadmilling

Actin filaments undergo polymerization and depolymerization from either end. The polymerization and depolymerization rates depend on the cytosolic concentration of free G-actins. The polymerization rate is generally higher at the plus or barbed end, while the depolymerization rate is higher at the minus or pointed end. At a steady state, critical concentration describes the concentration of free G-actin monomers at which the polymerization rate at the plus end is equal to that of the...
Pozzolans01:21

Pozzolans

Pozzolans are siliceous or aluminous materials blended with Portland cement. They interact with the calcium hydroxide produced during the hydration of Portland cement and contribute to improved strength and durability of concrete. The pozzolanic activity, a measure of a pozzolan's effectiveness, is typically assessed using the strength activity index, as defined in ASTM C 618-93, which calculates the ratio of the compressive strength of cement mixtures with and without pozzolan.
Fly ash is a...
Masonry Paving01:21

Masonry Paving

The construction of masonry paving involves using materials such as bricks, stones, and concrete masonry units. These materials are chosen for their shape, color, strength, and resistance to abrasion and weathering. Masonry units can be installed dry on a thin layer of sand and a gravel base, or they can be embedded in mortar or asphalt on a concrete slab. For areas subjected to heavy vehicular loads, a rigid base layer of reinforced or unreinforced concrete is recommended. In contrast,...
Rab Cascades01:25

Rab Cascades

Rab GTPases act in a regulated cascade during membrane fusion, helping the lipid bilayers mix. The Rab family of proteins are active when bound to GTP, and inactive when bound to GDP. Hence, they act as guanine nucleotide-dependent molecular switches. Rab-GTP recognizes and binds to long or short-range tethering proteins to capture the target vesicle. These tethers coordinate with SNAREs on the vesicle and the target membrane to assemble the trans SNARE complex that locks the mixing bilayers.
Porin Insertion in the Outer Mitochondrial Membrane01:12

Porin Insertion in the Outer Mitochondrial Membrane

Porins are beta-barrel proteins translocated to the mitochondrial outer membrane through the TOM complex into the intermembrane space. Porin precursors bind TIM chaperones within the intermembrane space and are guided to the Sorting and Assembly Machinery complex or SAM complex on the outer mitochondrial membrane.
Three models describe the assembly of porins by the SAM complex and their insertion into the outer membrane. Model 1 suggests that porins are assembled outside the SAM channel as the...

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相关实验视频

Updated: Jul 12, 2026

Isolating Mesangiogenic Progenitor Cells (MPCs) from Human Bone Marrow
09:53

Isolating Mesangiogenic Progenitor Cells (MPCs) from Human Bone Marrow

Published on: July 15, 2016

佩利山的活动.

A Heilprin

    Science (New York, N.Y.)
    |April 3, 1903
    PubMed
    概括

    No abstract available in PubMed .

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