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Updated: Jan 8, 2026

An Optical Assay for Synaptic Vesicle Recycling in Cultured Neurons Overexpressing Presynaptic Proteins
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An Optical Assay for Synaptic Vesicle Recycling in Cultured Neurons Overexpressing Presynaptic Proteins

Published on: June 26, 2018

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活性区蛋白RIM1的取决于Scrapper的无处不在调节了突触囊泡释放的过程

Ikuko Yao1, Hiroshi Takagi, Hiroshi Ageta

  • 1Mitsubishi Kagaku Institute of Life Sciences (MITILS), 11 Minamiooya, Machida, Tokyo 194-8511, Japan.

Cell
|September 7, 2007
PubMed
概括

SCRAPPER是一种新型的E3泛基因酶,通过降解RIM1.1,调节中枢神经系统的突触活动. 这一发现澄清了突触可塑性机制,并提供了新的治疗点.

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