跨吸管微创性大动脉植入:多中心体验
Thomas Walther1, Paul Simon, Todd Dewey
1University Leipzig, Heartcenter, Department of Cardiac Surgery, Leipzig, Germany. walt@medizin.uni-leipzig.de
Circulation
|September 14, 2007
概括
对高风险大动脉狭窄患者来说,微创性跨门大动脉植入 (TAP-AVI) 提供了安全的,早期的成功. 需要进一步的研究来评估长期结果并扩大其应用.
科学领域:
- 心血管外科心血管外科
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 大动脉狭窄带来了显著的风险,特别是对于高风险患者.
- 对这个患者群体来说,最少的侵入性手术选择至关重要.
研究的目的:
- 评估跨管主动脉植入 (TAP-AVI) 的初始多中心结果.
- 评估TAP-AVI在患有大动脉狭窄症的高风险患者的安全性和有效性.
主要方法:
- 这项研究涉及59名高风险患者,他们使用气球可扩展支架 (Edwards SAPIEN THV) 进行TAP-AVI.
- 手术是通过在跳动的心脏上进行微型胸腔切除术进行的,有或没有体外循环.
- 光镜和心声回声指导被用于门定位和评估.
主要成果:
- 在53名患者中成功实现了TAP门定位;4人需要转换为胸切除术.
- 没有出现冠状动脉阻塞或假肢迁移;所有门都表现出良好的血液动力学功能.
- 住院死亡率为13.6% (8名患者),与门功能障碍无关. 在随访时,精算生存率为75.7%.
结论:
- 穿越性大动脉植入 (TAP-AVI) 是一种安全的程序,对于高风险患者来说,它具有有前途的早期结果.
- 长期门性能和TAP-AVI的扩展应用需要进一步研究.
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