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Updated: May 2, 2026

Membrane-SPINE: A Biochemical Tool to Identify Protein-protein Interactions of Membrane Proteins In Vivo
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Membrane-SPINE: A Biochemical Tool to Identify Protein-protein Interactions of Membrane Proteins In Vivo

Published on: November 8, 2013

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C8alpha-MACPF的结构揭示了补充体免疫防御中的膜攻击机制

Michael A Hadders1, Dennis X Beringer, Piet Gros

  • 1Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.

Science (New York, N.Y.)
|September 18, 2007
PubMed
概括

哺乳动物的免疫蛋白,如补充膜攻击复合体 (MAC) 和穿孔素,在毛孔形成中使用共享的MACPF域. 结构分析揭示了与细菌细胞酶的同质性,表明一种共同的膜插入机制.

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