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Updated: Jul 11, 2026

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人类IgG4抗体的抗炎活性通过动态的Fab臂交换

Marijn van der Neut Kolfschoten1, Janine Schuurman, Mario Losen

  • 1Sanquin Research-AMC Landsteiner Laboratory, Department of Immunopathology, Plesmanlaan 125, 1066 CX Amsterdam, the Netherlands.

Science (New York, N.Y.)
|September 18, 2007
PubMed
概括

研究人员在免疫球蛋白G,同型4 (IgG4) 抗体中发现了一种新的抗体修饰. 这种称为Fab臂交换的修饰导致抗炎作用,挑战抗体的典型的炎症作用.

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