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Updated: Dec 21, 2025

Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.
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血细胞树突细胞感知自我DNA与抗菌素结合

Roberto Lande1, Josh Gregorio, Valeria Facchinetti

  • 1Department of Immunology, M. D. Anderson Cancer Center, University of Texas, Houston, Texas 77030, USA.

Nature
|September 18, 2007
PubMed
概括

抗微生物LL37通过使自身DNA触发Toll类受体9来激活血类树突细胞 (pDCs). 这种机制解释了对自我DNA的天生的耐受性如何在牛皮等自身免疫性疾病中崩.

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