扩大杀虫剂处理的床覆盖面对肯尼亚农村儿童生存率的影响:一项纵向研究
Greg W Fegan1, Abdisalan M Noor, Willis S Akhwale
1Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research-Coast, Kenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya. gfegan@kilifi.kemri-wellcome.org
Lancet (London, England)
|September 25, 2007
概括
在肯尼亚,用杀虫剂处理的床网显著降低了44%的儿童死亡率. 换句话说,每分发1000个ITN,大约有7人得救,这证实了它们在提高儿童存活率方面的有效性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 儿童生存率 儿童生存率
背景情况:
- 在随机对照试验中,被证明用杀虫剂处理的床网 (ITN) 可以改善儿童的生存率.
- 肯尼亚的ITN覆盖率从2004年的7%升至2006年的67%.
研究的目的:
- 评估ITN覆盖率增加对肯尼亚儿童存活率的影响.
- 评估ITN分销计划的实际有效性.
主要方法:
- 在肯尼亚的72个农村集群中,大约有3500名1-59个月的儿童参与了动态队列研究.
- 数据是在两年内每年三次收集的.
- 使用普森回归分析来评估ITN的影响,控制混变量.
主要成果:
- 在第一和第二个研究年之间,总体死亡率保持一致.
- 使用ITN与统计学上显著的44%的儿童死亡率降低有关 (MRR0.56,p=0.04).
- 据估计,每分发1000个ITN,就有7个死亡被避免.
结论:
- 该研究表明,社交营销和ITN大规模免费分发的结合导致儿童存活率的好处与随机对照试验中的好处相当.
- 这种现实世界的证据支持大规模ITN干预措施在减少儿童死亡率方面的有效性.
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