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Updated: Jun 19, 2026

MicroRNA-based Regulation of Picornavirus Tropism
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Published on: February 6, 2017

有效的RNAi介导基因沉默,而不会中断内源微RNA路径

Matthias John1, Rainer Constien, Akin Akinc

  • 1Alnylam Europe AG, Fritz-Hornschuch-Str. 9, 95326 Kulmbach, Germany.

Nature
|September 28, 2007
PubMed
概括

合成小干扰RNAs (siRNAs) 的系统性管理有效地使肝脏中的基因沉默,而不会影响自然的microRNA (miRNA) 途径. 这项研究支持合成siRNA作为动物研究中基因沉默的安全治疗工具.

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