白天与夜间门诊血压的预后准确性:一个队列研究
José Boggia1, Yan Li, Lutgarde Thijs
1Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
Lancet (London, England)
|October 9, 2007
概括
夜间血压是死亡率的强有力的预测指标,即使考虑到白天的读数. 推全天随行血压监测,以进行全面的心血管风险评估.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 预防医学 预防医学
背景情况:
- 与白天读数相比,夜间血压的独立预测值存在有限的研究.
- 夜间至日间血压比率的预后意义需要进一步调查.
研究的目的:
- 为了评估在白天和夜晚的门诊血压的预后意义.
- 评估夜间至日间血压比对死亡率和心血管事件的预测价值.
主要方法:
- 在六个国家的7458名个人中进行了24小时的门诊血压监测.
- 经多变量调整的危险比率计算为白天,夜间血压,缩性夜间到白天的比率,控制共变量.
主要成果:
- 夜间血压独立预测了总,心血管和非心血管死亡率.
- 日间血压,调整为夜间读数,预测非心血管死亡率和所有心血管事件.
- 缩性夜间到日间比率为1或更高与增加的死亡风险有关.
结论:
- 当调整为夜间读数时,白天血压保留了心血管事件的预后价值,除了接受治疗的患者.
- 这些发现支持在整个24小时内定期记录门诊血压.
- 夜间血压升高可能表明反向因果关系,需要进一步研究.
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