美国的入侵性甲素耐药黄金葡萄球菌感染
R Monina Klevens1, Melissa A Morrison, Joelle Nadle
1Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. rmk2@cdc.gov
JAMA
|October 18, 2007
概括
侵入性甲素耐药黄金葡萄球菌 (MRSA) 感染是一个重大的公共卫生问题,不成比例地影响老年人,黑人和男性. 这些感染主要与医疗保健相关,但越来越多地出现在传统医院环境之外.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 由于流行病学的发展,准确的数据对美国抗甲素黄金葡萄球菌 (MRSA) 感染的范围至关重要.
- 了解侵入性MRSA的负担对于公共卫生战略至关重要.
研究的目的:
- 为了确定侵入性MRSA疾病在美国9个社区的发病率和分布.
- 估计2005年美国入侵性MRSA感染的总负担.
主要方法:
- 从2004年7月到2005年12月,在美国9个地区进行了基于人群的侵入性MRSA监测.
- 研究MRSA病例并将其分类为与医疗保健相关的 (医院发病或社区发病) 或与社区相关的.
- 分析了MRSA菌株的发病率,死亡率和分子特征.
主要成果:
- 报告共有8987例侵入性MRSA病例. 大多数是与医疗保健相关的 (85%),其中58.4%的社区发病率和26.6%的医院发病率.
- 2005年入侵性MRSA的标准化发病率为每10万人口中的31.8.
- 发病率在65岁以上的个人,黑人个人和男性中是最高的. 标准化死亡率为每10万人的6.3.
结论:
- 侵入性MRSA感染对特定人群的影响不成比例,突出了健康差异.
- 虽然MRSA仍然是一个主要的公共卫生问题,主要与医疗保健机构有关,但也超出了传统的局限.
- 分子分析显示,在所有监测区域的医疗保健相关感染中存在社区相关的MRSA菌株.
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