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Updated: Jul 10, 2026

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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微信E492m的生物合成定制:翻译后的修改提供了抗菌的 siderophore-peptide 结合体

Elizabeth M Nolan1, Michael A Fischbach, Alexander Koglin

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|November 2, 2007
PubMed
概括

四种蛋白质修改了微信E492 (MccE492),这是来自Klebsiella pneumoniae的毒素. 它们将一种修改后的肠杆菌素 (铁除菌素) 附着在MccE492上,从而产生一种强大的抗菌剂.

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