适度的能量缺乏是好的吗?
Christoph Freyer1, Nils-Göran Larsson
1Department of Laboratory Medicine, Karolinska Institutet, 141 86, Stockholm, Sweden.
Cell
|November 6, 2007
概括
减少线粒体氧化酸化可以保护小鼠免受肥胖和糖尿病的影响. 这表明,胰岛素耐药人类氧化酸化受损可能是一种补偿机制,而不是糖尿病的原因.
科学领域:
- 代谢研究的研究.
- 线粒体功能 线粒体功能
- 糖尿病和肥胖症研究研究.
背景情况:
- 线粒体氧化化 (OXPHOS) 对于细胞能量生产至关重要.
- 胰岛素抵抗与外围组织中OXPHOS受损有关.
- 在糖尿病和肥胖的发病过程中,OXPHOS缺乏的作用仍然不清楚.
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