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雷布通过对抗其内源性抑制剂FKBP38来激活mTOR

Xiaochun Bai1, Dongzhu Ma, Anling Liu

  • 1Department of Pharmacology, University of Pittsburgh School of Medicine, E1357 Biomedical Science Tower, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

Science (New York, N.Y.)
|November 10, 2007
PubMed
概括

哺乳动物的目标拉巴胺素 (mTOR) 控制细胞生长,并由Rheb. 雷布阻止FKBP38抑制mTOR,揭示了细胞生长的新调节途径.

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