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CRISPR-Mediated Reorganization of Chromatin Loop Structure
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基因组重组途径的RNA介导的表观遗传编程

Mariusz Nowacki1, Vikram Vijayan, Yi Zhou

  • 1Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA.

Nature
|November 30, 2007
PubMed
概括

在Oxytricha trifallax中,RNA分子作为模板,在发育过程中指导大规模的DNA基因组重组. 这种表观遗传机制确保了精确的DNA组装,这对于体质基因组形成至关重要.

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