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mTOR通过YY1-PGC-1alpha转录复合体控制线粒体的氧化功能.

John T Cunningham1, Joseph T Rodgers, Daniel H Arlow

  • 1Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|November 30, 2007
PubMed
概括

猛素 (mTOR) 的哺乳动物点对线粒体的氧化功能至关重要. mTOR通过转录因子YY1调节线粒体基因表达和氧气消耗,影响能量恒温.

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