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Updated: Jul 9, 2026

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
07:23

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome

Published on: June 15, 2016

从抑制转向激活:microRNAs可以对翻译进行上调

Shobha Vasudevan1, Yingchun Tong, Joan A Steitz

  • 1Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06536, USA.

Science (New York, N.Y.)
|December 1, 2007
PubMed
概括

微RNAs (miRNAs) 可以通过与信使RNA (mRNA) 中的AU丰富元素 (AREs) 结合来激活细胞周期停止期间的基因翻译. 微核核蛋白 (miRNP) 的这种激活功能似乎随着细胞增殖而波动.

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