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重定向真菌聚基酸合成酶的循环化步骤

Suzanne M Ma1, Jixun Zhan, Xinkai Xie

  • 1Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California 90095, USA.

Journal of the American Chemical Society
|December 13, 2007
PubMed
概括

研究人员通过改变 thioesterase/claisen cyclase (TE/CLC) 域来重定向真菌聚基酸合成酶 (PKS) 循环化步骤. 这使得新型多基基的合成成为可能,并证明了结合真菌和细菌PKS组件的潜力.

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