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Updated: Jul 9, 2026

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皮尔尼埃克西默信号分子信标用于探测核酸

Patrick Conlon1, Chaoyong James Yang, Yanrong Wu

  • 1Center for Research at Bio/Nano Interface, Department of Chemistry and Shands Cancer Center, University of Florida Genetics Institute, University of Florida, Gainesville, Florida 32611-7200, USA.

Journal of the American Chemical Society
|December 15, 2007
PubMed
概括

具有多个pyrene单体的工程分子信标 (MBs) 提供敏感的实时DNA检测. 这种新的探针设计增强了光信号,以改善DNA序列分析.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...