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Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity
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与氨酸激酶抑制剂sunitinib相关的心脏毒性

Tammy F Chu1, Maria A Rupnick, Risto Kerkela

  • 1Department of Cardiology, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA.

Lancet (London, England)
|December 18, 2007
PubMed
概括

苏尼提尼布治疗胃肠道 stromal 瘤可能会导致心血管事件,包括心力衰竭和左心室喷射率 (LVEF) 降低. 建议在接受sunitinib的患者中密切监测高血压和LVEF变化.

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