相关实验视频

坚持地中海饮食与中年男性循环中白素-6相反相关:一项双胞胎研究

Jun Dai¹, Andrew H Miller, J Douglas Bremner

¹Nutrition and Health Sciences Program, Emory University School of Medicine, Atlanta, Ga, USA.

|December 19, 2007

概括

坚持地中海饮食可显著降低胰岛素中白素-6水平,这是炎症的标志物. 这种关联主要是由个人的生活方式选择驱动的,而不是共同的遗传或家庭因素,支持其心血管益处.

科学领域:

心血管疾病的研究研究.
营养科学营养科学
炎症生物学炎症生物学

背景情况:

地中海饮食与降低心血管疾病风险有关.
提出的一个关键机制是减少全身炎症.
在这种关联中,遗传与家族因素的作用仍然不清楚.

研究的目的:

调查遵守地中海饮食和炎症生物标志物之间的关系.
为了区分共同的遗传/家庭因素与个人生活方式选择的贡献.

主要方法:

在345名中年男性双胞胎中使用了威利特食物频率调查问卷.
评估了地中海饮食的坚持,并测量了白蛋白-6和C反应蛋白的血水平.
采用混合效应回归分析来检查饮食与炎症的关联,控制共变量.

主要成果:

对地中海饮食的更高坚持与较低的互白素-6水平 (P<0.001) 有意义地相关.
对于C反应蛋白 (P=0.10) 没有发现显著的关联.
在对内分析显示了非常显著的效应 (P<0.0001),表明个人坚持是关键因素,而不是共享因素.

结论:

共同的环境和遗传因素并不能显著解释饮食与炎症的联系.
个人坚持地中海饮食与减少炎症有很强的相关性.
这支持减轻炎症,作为饮食心血管保护作用的关键机制.

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