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Updated: May 5, 2026

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缺陷的托芬代谢是小鼠慢性粒状瘤疾病的基础炎症

Luigina Romani1, Francesca Fallarino, Antonella De Luca

  • 1Department of Experimental Medicine, University of Perugia, 06126 Perugia, Italy. lromani@unipg.it

Nature
|January 11, 2008
PubMed
概括

慢性颗粒状瘤疾病 (CGD) 损害了免疫细胞因NADPH氧化酶缺乏而对抗感染的能力. 这项研究揭示了受阻的金氨酸通路,导致炎症,可以通过恢复通路功能来逆转.

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