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相关概念视频

Frequency-dependent Selection01:21

Frequency-dependent Selection

When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.Positive Frequency-Dependent SelectionIn positive...
Dosage Compensation02:50

Dosage Compensation

In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will have...
Types of Selection01:46

Types of Selection

Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...

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相关实验视频

Updated: Jul 8, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

在C. elegans中广泛存在的遗传不相容性,通过平衡选择来维持.

Hannah S Seidel1, Matthew V Rockman, Leonid Kruglyak

  • 1Lewis-Sigler Institute for Integrative Genomics and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. hseidel@princeton.edu

Science (New York, N.Y.)
|January 12, 2008
PubMed
概括

遗传不相容性通常通过自然选择消除. 然而,对Caenorhabditis elegans的一项研究发现了持续的不相容性,这表明平衡的多态性维持了这种遗传冲突.

科学领域:

  • 进化遗传学的进化遗传学
  • 人口遗传学 人口遗传学
  • 分子生物学分子生物学

背景情况:

  • 自然选择通常会消除交杂种群之间的遗传不相容性.
  • 遗传不相容性可能会对生物体的健康产生负面影响.

研究的目的:

  • 为了调查全球分布的 Caenorhabditis elegans. 的遗传不相容性.
  • 了解进化机制,尽管健身成本,保持这种不兼容性.

主要方法:

  • 对链接的 loci zeel-1 和 peel-1 的种群遗传分析.
  • 对序列分歧和链接不平衡的检查.
  • 评估不兼容性对健康的后果.

主要成果:

  • 确定了zeel-1和peel-1等位基因之间的特定不兼容性.
  • 不兼容的等位基因紧密联系在一起,并且在常见的单位基因类型中发现.
  • 自然选择积极保护这些单元类型,保持不相容性.

结论:

  • 涉及连接位置的平衡多态性保留了Caenorhabditis elegans的遗传不相容性.

更多相关视频

Manipulation of Ploidy in Caenorhabditis elegans
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Manipulation of Ploidy in Caenorhabditis elegans

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Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

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相关实验视频

Last Updated: Jul 8, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

  • 这种平衡的多态性仍然存在,尽管基因流和负面的健康影响.