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在真核生物中对内子拼接的转化控制

Olivier Jaillon1, Khaled Bouhouche, Jean-François Gout

  • 1Genoscope (CEA), 2 rue Gaston Crémieux CP5706, 91057 Evry, France.

Nature
|January 19, 2008
PubMed
概括

细胞基因使用拼接来去除内子,但准确性仍然是一个挑战. 这项研究揭示了无意义介导的mRNA衰变 (NMD) 有助于通过降解有缺陷的转录来确保适当的基因表达,特别是在具有许多内子的物种中.

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