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Updated: Apr 30, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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凝聚素通过CCCTC-结合因子调节转录绝缘

Kerstin S Wendt1, Keisuke Yoshida, Takehiko Itoh

  • 1Research Institute of Molecular Pathology, Dr. Bohr Gasse 7, 1030 Vienna, Austria.

Nature
|February 1, 2008
PubMed
概括

凝聚蛋白是一种蛋白质复合体,通过与CTCF合作来调节基因表达,作为转录绝缘体. 这一功能,独立于细胞分裂,可能会在像康奈莉亚·德朗格综合征这样的凝聚性病变中受损.

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