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Updated: Jul 7, 2026

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
09:16

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells

Published on: September 1, 2019

在细胞毒性T细胞发育过程中,Runx复合体抑制转录因子Th-POK

Ruka Setoguchi1, Masashi Tachibana, Yoshinori Naoe

  • 1Laboratory for Transcriptional Regulation, RIKEN Research Center for Allergy and Immunology, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.

Science (New York, N.Y.)
|February 9, 2008
PubMed
概括

运行转录因子通过抑制Th-POK表达来积极抑制T辅助细胞的发展. 这允许CD8+细胞毒性T细胞的分化,这对适应性免疫至关重要.

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Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Published on: May 17, 2016

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