在高血压患者中进行二皮里达摩尔心声压力测试. 目标和工具 目标和工具
A R Lucarini1, E Picano, F Lattanzi
1CNR Clinical Physiology Institute, University of Pisa, Italy.
Circulation
|May 1, 1991
概括
动脉高血压通过冠状动脉疾病,左心室缩或微血管疾病影响冠状动脉流量储备. 每个人的诊断标记都不同,在二皮里达摩尔测试期间的心电图和心电图变化提供了不同的见解.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 诊断成像 诊断成像 诊断成像
背景情况:
- 动脉高血压可以通过多种途径减少冠状动脉流量储备,包括冠状动脉疾病,左心室缩和微血管功能障碍.
- 有效的诊断需要针对这些高血压标的不同标记物.
- 了解这些机制对于管理高血压患者心血管风险至关重要.
研究的目的:
- 研究特定诊断标记在区分动脉高血压中冠状动脉流量储备减少的机制时的有用性.
- 评估二维心声和心电图在高血压患者的二皮里达摩尔输液期间的可靠性.
主要方法:
- 在二皮里达摩尔输注期间利用二维回声心脏图像来评估作为冠状动脉疾病标志物的短暂失能.
- 分析了与血管学评估的冠状动脉疾病,左心室缩和微血管疾病相关的二皮里达摩尔诱导的ST段抑郁.
- 相关的心电学发现与心声学评估和冠状动脉流量储备测量在节拍过程中.
主要成果:
- 声心成像中的短暂不协同可靠地识别了在正常血压和高血压患者中冠状动脉疾病.
- 在高血压患者中,二皮里达摩尔诱导的ST段抑郁通常在没有显著的冠状动脉疾病的情况下发生,并且可能与左心室缩有关.
- 即使在正常的左心室质量下,ST段抑郁也与冠状动脉流量储备受损相关,这表明微血管疾病.
结论:
- 心声学可以有效地检测高血压个体的冠状动脉疾病.
- 在高血压中进行二皮里达摩尔测试时的心电图变化可能表明左心室缩或微血管疾病,即使没有阻塞性冠状动脉疾病.
- 超高血压中心声静态电心图变化的临床意义需要进一步调查,以确定它们作为早期心肌损伤标志物的作用.
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