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Mg2+在子头核酶催化中的作用来自分子模拟的分子模拟

Tai-Sung Lee1, Carlos Silva López, George M Giambasu

  • 1Consortium for Bioinformatics and Computational Biology, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, USA.

Journal of the American Chemical Society
|February 15, 2008
PubMed
概括

(Mg2+) 离子对于头 рибо酶 (HHRz) 催化非常重要,稳定关键结构和过渡状态. 模拟显示Mg2+通过协调必要的催化残留物来促进RNA裂变.

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