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Updated: May 11, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
11:44

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Published on: January 24, 2016

通过IRF-7对先天免疫反应的转化控制

Rodney Colina1, Mauro Costa-Mattioli, Ryan J O Dowling

  • 1Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec H3G 1Y6, Canada.

Nature
|February 15, 2008
PubMed
概括

翻译抑制剂4E结合蛋白 (4E-BPs) 通常抑制I型干扰素 (IFN) 的产生. 移除4E-BPs可以通过增加干扰素调节因子7 (Irf7) 翻译来促进IFN生产,从而增强抗病毒免疫力.

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