选择性作弊突变体揭示了社会虫合作的遗传复杂性
Lorenzo A Santorelli1, Christopher R L Thompson, Elizabeth Villegas
1Department of Ecology and Evolutionary Biology, Rice University, Houston, Texas 77005, USA.
Nature
|February 15, 2008
概括
进化中的合作很容易受到"骗子"突变分子的攻击. 在社会虫中进行全基因组选时,发现了100多个与作弊相关的基因,其中许多基因是选择性的.
科学领域:
- 进化生物学是进化的生物学.
- 遗传学 是一个遗传学.
- 社会行为社会行为.
背景情况:
- 合作是主要进化转型的基础,如多细胞性和eusociality.
- 合作系统的稳定性受到"骗子"突变物出现的威胁,这些突变物利用合作而不是贡献.
- 选择性欺骗,即突变者欺骗非亲属,但与亲属合作,可以保持合作.
研究的目的:
- 为了对作弊的遗传基础进行基因组规模的调查.
- 识别使作弊行为成为可能的基因和遗传途径.
- 了解在社会生物体中作弊的遗传机会的普遍性和性质.
主要方法:
- 在一个社会虫模型系统中进行了全基因组选.
- 在整个生物体的基因组中发现了赋予作弊表型的突变.
- 欺骗行为在嵌合体和克隆环境中进行了评估.
主要成果:
- 发现超过100种不同类型的基因与作弊有关.
- 许多已识别的作弊突变体表现出学术作弊,在克隆群体中合作,但在仿真体中作弊.
- 这揭示了在全基因组范围内作弊的多方面的遗传机会.
结论:
- 现型稳定的合作系统可能存在潜在的遗传冲突.
- 欺骗的遗传结构复杂,涉及许多基因和途径.
- 进化冲突和反冲突的机会可能会推动参与社会相互作用的多个基因的选择.
相关概念视频
Protein Complexes with Interchangeable Parts
2.1K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.1K
Diversity of Protists I
2.3K
Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
2.3K
Diversity of Protists IV
2.1K
Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...
2.1K
Evolutionary Processes in Microbes
202
Microbial evolution occurs rapidly due to short generation times and a variety of genetic processes, including horizontal gene transfer, mutation, recombination, and genetic drift. These mechanisms collectively enable microbes to adapt swiftly to changing environments.Horizontal gene transfer (HGT) allows genes to move between different species and occurs through three main mechanisms: conjugation, transformation, and transduction. Conjugation involves direct cell-to-cell contact for DNA...
202
Evolution of New Traits in Microbes
199
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
199
Microbial Interactions: Cooperation
59
Microbial cooperation involves beneficial interactions in which different species work together for individual or mutual advantage. These interactions can profoundly influence ecological dynamics and evolutionary processes, and they are essential to many pathogenic and symbiotic relationships.Nematode–Bacteria CooperationA striking example is the relationship between the Gram-negative bacterium Xenorhabdus nematophila and the parasitic nematode Steinernema carpocapsae. Juvenile nematodes...
59


