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Isolation of Ribosome Bound Nascent Polypeptides in vitro to Identify Translational Pause Sites Along mRNA
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一个基变形酶-核糖体复合体揭示了新生的链处理机制

Rouven Bingel-Erlenmeyer1, Rebecca Kohler, Günter Kramer

  • 1Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.

Nature
|February 22, 2008
PubMed
概括

变形酶 (PDF) 通过其C端延伸直接与细菌核糖体相互作用,使新生蛋白质的高效协同翻译处理成为可能. 这种相互作用增强了细胞活力,并为蛋白质合成提供了结构性见解.

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