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Updated: Jul 7, 2026

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
08:40

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library

Published on: April 6, 2012

通过Lin28对微RNA处理进行选择性阻断

Srinivas R Viswanathan1, George Q Daley, Richard I Gregory

  • 1Stem Cell Program, Children's Hospital Boston, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02115, USA.

Science (New York, N.Y.)
|February 23, 2008
PubMed
概括

林28蛋白阻断胚胎细胞中let-7微RNAs (miRNAs) 的处理. 这一发现揭示了Lin28作为miRNA生物发生的负调节者,影响干细胞分化和癌症.

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