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UNC93B1将核酸感应的收费类受体传递给内解体体

You-Me Kim1, Melanie M Brinkmann, Marie-Eve Paquet

  • 1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA. ykim@wi.mit.edu

Nature
|February 29, 2008
PubMed
概括

蛋白质UNC-93B1对于将收费类受体 (TLRs) 7和9从内分泌网膜运输到内分泌体至关重要,从而使免疫反应成为可能. 这一发现允许对这些特定的TLR进行有针对性的调节.

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