相关实验视频

Updated: Jul 6, 2026

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation
09:37

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation

Published on: March 15, 2018

氨酸激酶Btk和Tec通过链接RANK和ITAM信号来调节骨质细胞分化

Masahiro Shinohara1, Takako Koga, Kazuo Okamoto

  • 1Department of Cell Signaling, Graduate School, Tohoku University, Seiryo-machi 4-1, Aoba-ku, Sendai, Miyagi 980-8575, Japan.

Cell
|March 11, 2008
PubMed
概括

缺少特定的氨酸激酶 (Btk和Tec) 的小鼠由于骨质细胞功能受损而表现出骨质疏松症. 这项研究揭示了涉及这些激酶的关键信号复合体,为骨疾病提供了潜在的治疗点.

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Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model08:42

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Published on: July 3, 2020

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