在自然种群中适应性差异的遗传基础
1Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden. hans.ellegren@ebc.uu.se
Nature
|March 14, 2008
概括
基因组学有助于确定影响健康和自然选择的特征的遗传基础. 这推动了我们对基因型-表型关系和野生种群的定量变异的理解.
科学领域:
- 进化生物学 进化生物学
- 基因组学就是基因组学.
- 量化遗传学 量化遗传学
背景情况:
- 基因组学彻底改变了生物学的研究.
- 识别适应性特征的遗传基础对于理解自然选择至关重要.
- 基因型-表型关系是进化过程的关键.
研究的目的:
- 探索基因组学在识别健康相关特征的遗传基础中的作用.
- 合成进化生物学中的生态和分子方法.
- 研究自然种群中的基因型-表型关系.
主要方法:
- 利用不同的基因组方法.
- 分析基因型-表型关系.
- 研究自然种群的定量变化.
主要成果:
- 基因组研究已经成功地在自然种群中建立了基因型-表型关系.
- 获得了对定量变异遗传结构的新见解.
- 在理解野生健康变化的定量遗传学的进步.
结论:
- 基因组学为研究适应和进化提供了强大的工具.
- 生态和分子数据的合成正在进化生物学中出现.
- 了解健身的遗传基础正在迅速发展.
相关概念视频
Inclusive Fitness
Most altruistic behavior—in which one animal helps another at a cost to themselves—occurs between relatives. Scientists think these altruistic behaviors evolved because they increase the inclusive fitness of the animal providing help.
What is Population Genetics?
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
Mutation, Gene Flow, and Genetic Drift
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
Genetics of Speciation
Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
Gene Flow
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
Natural Selection and Mating Preferences
The principle of natural selection posits that organisms better adapted to their environment are more likely to survive and reproduce. This principle is closely intertwined with mating preferences, a key aspect of sexual selection, which evolutionary psychologists believe is driven by instincts to propagate one's genes. Such instincts significantly influence mating behaviors and preferences between genders.
Females, due to their biological roles in conception, pregnancy, and nursing, inherently...
Females, due to their biological roles in conception, pregnancy, and nursing, inherently...


