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Updated: May 31, 2026

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通过siRNA通过TLR3抑制序列和目标独立的血管生成

Mark E Kleinman1, Kiyoshi Yamada, Atsunobu Takeda

  • 1Department of Ophthalmology, University of Kentucky, Lexington, Kentucky 40506, USA.

Nature
|March 28, 2008
PubMed
概括

小干扰RNA (siRNA) 通过通用类受体3 (TLR3) 抑制胆道新血管化 (CNV),而不是基因沉默. 这一发现表明,通用siRNAs可以通过激活TLR3,独立于针对特定基因来治疗血管性疾病.

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