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Updated: Jul 6, 2026

Assaying Protein Kinase Activity with Radiolabeled ATP
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Assaying Protein Kinase Activity with Radiolabeled ATP

Published on: May 26, 2017

使用表达蛋白质结合和计算建模分析蛋白质激酶自化

Kerry A Pickin1, Sidhartha Chaudhury, Blair C R Dancy

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, Maryland 21210, USA.

Journal of the American Chemical Society
|April 10, 2008
PubMed
概括

这项研究揭示了蛋白质激酶A (PKA) 自酸化发生在血清338.8的分子内. 研究人员使用蛋白质半合成来证明PKA中这种独特的调节机制.

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Protein Kinases and Phosphatases

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Phosphorylation

The addition or removal of phosphate groups from proteins is the most common chemical modification that regulates cellular processes. These modifications can affect the structure, activity, stability, and localization of proteins within cells as well as their interactions with other proteins.
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