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Updated: May 6, 2026

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BCR-ABL1淋巴细胞白血病的特点是删除Ikarosos

Charles G Mullighan1, Christopher B Miller, Ina Radtke

  • 1Department of Pathology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Nature
|April 15, 2008
PubMed
概括

由于IKZF1删除,Ikaros功能的丧失对于发展BCR-ABL1阳性急性淋巴细胞白血病 (ALL) 至关重要. 这与慢性骨髓性白血病 (CML) 相反,其中IKZF1缺失缺失.

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