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Updated: May 10, 2026

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
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Published on: October 28, 2014

在无意义介导的mRNA衰变过程中,Upf1酸化触发了转化抑制

Olaf Isken1, Yoon Ki Kim, Nao Hosoda

  • 1Department of Biochemistry and Biophysics, School of Medicine and Dentistry, 601 Elmwood Avenue, Box 712, University of Rochester, Rochester, NY 14642, USA.

Cell
|April 22, 2008
PubMed
概括

无意中介的mRNA衰变 (NMD) 涉及化Upf1抑制翻译启动因子eIF3. 这阻止了进一步的翻译,标记了转录的退化.

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