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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
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胸腔腹腔动脉瘤的内血管修复
1Department of Vascular Surgery, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA. greenbr@ccf.org
Circulation
|April 30, 2008
概括
胸腔腹腔动脉瘤的内血管修复提供了一个可行的替代方案,降低死亡率. 像窗式支架移植这样的先进技术在复杂的大动脉疾病中显示出有前途的安全性和有效性.
科学领域:
- 血管外科 血管外科
- 医疗器械 医疗器械
- 大动脉动脉瘤治疗方法
背景情况:
- 传统的胸腔腹腔动脉瘤修复带来了高的发病率和死亡率.
- 正在探索替代性内血管技术以改善患者的治疗结果.
研究的目的:
- 审查和报告用于胸腔腹腔动脉瘤修复的替代性内血管技术.
- 评估这些新方法的可行性,安全性和有效性.
主要方法:
- 对带有窗体和分支的内血管移植进行检查,用于内脏血管的结合.
- 对涉及外解剖绕道和大动脉支架移植的混合程序的分析.
- 对已发表的案例系列和结果进行表化和审查.
主要成果:
- 混合程序显示可行性,但死亡率高 (高达25%).
- 针对副侧脉动动脉瘤的fenestrated支架移植在中期结果中显示出安全性和有效性.
- 对于胸腔腹腔动脉瘤的纯内血管方法,在较大的系列中报告了3-6%的术后死亡率.
结论:
- 胸腔腹腔动脉瘤的内血管修复是可行的,并降低了术后死亡率.
- 混合手术可能只适用于高风险患者;具有分支的进化内移植显示出有前途.
- 对于先进的内血管器械,需要在临床试验中进一步评估.
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