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Updated: May 19, 2026

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
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Cl-/H+ 反载体 ClC-7 是 lysosomes 中的主要化物浸透通道

Austin R Graves1, Patricia K Curran, Carolyn L Smith

  • 1Membrane Transport Biophysics Unit, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Building 35, MSC 3701, Bethesda, Maryland 20892, USA.

Nature
|May 2, 2008
PubMed
概括

通道7 (ClC-7) 作为一种重要的Cl-/H+抗载体,促进了溶酶体的酸化. 这项研究确定了ClC-7是溶酶体中主要的离子载体,对细胞降解和功能至关重要.

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