血压相关疾病的全球负担,2001年
Carlene M M Lawes1, Stephen Vander Hoorn, Anthony Rodgers
1Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand.
Lancet (London, England)
|May 6, 2008
概括
高血压导致全球760万死亡和9200万残疾调整寿命年 (DALYs). 这种负担不成比例地影响低收入国家和高血压前期患者,而不仅仅是那些被诊断患有高血压的人.
科学领域:
- 全球健康 全球健康
- 流行病学 流行病学
- 心血管疾病研究研究
背景情况:
- 关于高血压的全球分布和影响的数据有限.
- 高血压是导致全球疾病负担的重要因素,但仍未得到充分量化.
研究的目的:
- 为了估计全球的疾病负担归因于高血压.
- 分析这种负担按年龄,性别和经济地位的分布.
主要方法:
- 利用2001年的数据来估计与高血压相关的全球疾病负担 (静脉压>=115毫米升).
- 使用平均静脉血压,死亡率,残疾调整寿命年 (DALYs) 和回归稀释偏差调整的相对风险计算的人口影响分数.
- 按年龄 (>=30岁),性别和世界银行地区分层分析.
主要成果:
- 高血压与760万个过早死亡 (13.5%的全球总数) 和9200万个DALY (6.0%的全球总数) 相关.
- 可归因的疾病包括54%的全球中风和47%的缺血性心脏病.
- 大多数负担 (80%) 发生在低收入和中等收入经济体,超过一半影响了45-69岁的个人.
结论:
- 全球高血压疾病负担主要影响低收入和中等收入国家和中年人群.
- 负担的很大一部分与前高血压有关,这表明只针对高血压患者的策略是不够的.
- 公共卫生干预措施应扩大其范围,超越被诊断的高血压,以有效地减少整体疾病负担.
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