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Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time
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Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time

Published on: May 30, 2021

囊泡和小胞结合的α-synuclein中的破裂螺旋:来自现场定向旋转标记-EPR实验和MD模拟的见解

Marco Bortolus1, Fabio Tombolato, Isabella Tessari

  • 1Dipartimento di Scienze Chimiche, Università di Padova, via Marzolo, 1, 35131 Padova, Italy.

Journal of the American Chemical Society
|May 7, 2008
PubMed
概括

阿尔法-协同核蛋白是一种

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Overview of Secretory Vesicles01:33

Overview of Secretory Vesicles

Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...