相关实验视频
Updated: Apr 28, 2026

08:57
Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
Published on: August 14, 2018
14.3K
对鱼的基因组分析揭示了进化过程中独特的特征
Wesley C Warren1, LaDeana W Hillier, Jennifer A Marshall Graves
1Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA. wwarren@wustl.edu
Nature
|May 10, 2008
概括
鸟基因组揭示了基因创新,解释了其独特的爬行动物和哺乳动物特征. 这种单基体序列为人们提供了关于毒素,牛奶生产和免疫系统演变的见解.
科学领域:
- 基因组学就是基因组学.
- 进化生物学 进化生物学
- 哺乳动物遗传学 哺乳动物遗传学
背景情况:
- 鸟 (Ornithorhynchus anatinus) 是一个独特的单体动物,表现出爬行动物和哺乳动物特征的混合.
- 这些包括产卵,雄性中毒的产生,雌性中哺乳期,提出了进化问题.
研究的目的:
- 提出一项关于白类动物基因组序列的草案.
- 为了确定其独特的生物特征的遗传基础.
- 为比较哺乳动物基因组学提供资源.
主要方法:
- 关于Ornithorhynchus anatinus的全基因组测序.
- 基因家族的生物信息分析,包括蛋白质编码基因,非编码RNA和微RNA.
- 与其他脊椎动物进行基因组比较分析.
主要成果:
- 鉴定用于毒素生产的被选用基因家族,类似于爬行动物.
- 尽管产卵,但保留牛奶蛋白基因的确认.
- 发现与白生物学相关的扩大免疫基因家族.
- 蛋白质,RNA和重复元素家族中的扩张的表征.
结论:
- 鸟基因组为它的特征马赛克提供了遗传基础.
- 它强调了毒素的独立进化和哺乳基因的保存.
- 这种基因组资源对于理解哺乳动物进化和单种动物保护至关重要.
相关概念视频
The Evidence for Evolution
39.8K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
39.8K
Convergent Evolution
27.6K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
27.6K
Gene Evolution - Fast or Slow?
6.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
6.2K
Genome Size and the Evolution of New Genes
7.5K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
7.5K
Evolutionary Relationships through Genome Comparisons
5.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.8K
Gene Duplication and Divergence
6.8K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
6.8K

