TNF-αcaspase-8.

Lai Wang1, Fenghe Du, Xiaodong Wang

  • 1Howard Hughes Medical Institute and Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.

Cell
|May 20, 2008
PubMed
概括

瘤坏死因子-α (TNF-α) 通过两个不同的途径触发细胞亡. 这些途径包括cycloheximide或Smac仿真,通过cIAP1/2和c-FLIP差异调节caspase-8激活.

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