头癌是头部和部的癌症.
Athanassios Argiris1, Michalis V Karamouzis, David Raben
1Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15232, USA.
Lancet (London, England)
|May 20, 2008
概括
头部和部状细胞癌 (HNSCC) 通常与烟草和酒精有关. 治疗重点是生存和器官保存,使用手术,放射和全身疗法.
科学领域:
- 在瘤学瘤学.
- 头部和部手术 头部和部手术
- 癌症研究 癌症研究
背景情况:
- 头癌 (HNSCC) 主要来自上空消化表皮.
- 暴露于致癌物 (烟草,酒精) 和人类乳头瘤病毒是关键的病因因素.
- 治疗旨在提高生存率,同时由于复杂的解剖学,保持器官功能.
研究的目的:
- 审查HNSCC.的流行病学和分子病原性.
- 讨论当前的诊断和分期方法.
- 概述HNSCC最新的多式联运管理策略.
主要方法:
- 对流行病学数据和分子致病学研究的审查.
- 对诊断和分期标准的分析.
- 评估当前的治疗方式,包括手术,放射治疗,化疗和向治疗.
主要成果:
- 手术技术和放射治疗的重大进展.
- 成功整合化学疗法和表皮生长因子受体抑制剂等全身疗法.
- 多学科合作对于最佳的患者管理至关重要.
结论:
- 对于HNSCC的管理,需要采用多模式的方法,考虑患者特定的因素.
- 治疗决策平衡瘤学结果与功能性保存.
- 目前正在进行的研究继续改进HNSCC治疗策略.
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